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Endocannabinoid-gene

(2009) Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effects. Genes Brain Behav 8: 728–732.

Artificial Neural Network to Predict Varicocele Impact on Male Artificial Neural Network to Predict Varicocele Impact on Male Fertility through Testicular Endocannabinoid Gene Expression Profiles Davide Perruzza, Nicola Bernabò, Cinzia Rapino, Luca Valbonetti, Ilaria Falanga, Valentina Russo, Annunziata Mauro, Paolo Berardinelli, Liborio Stuppia, Mauro Maccarrone , Barbara Barboni Association between cerebral cannabinoid 1 receptor availability Although of great public health relevance, the mechanisms underlying disordered eating behavior and body weight regulation remain insufficiently understood. Compelling preclinical evidence GcMAF – Natural Immunotherapy Normalizes endocannabinoid gene expression (Siniscalco D, 2014 April). Induces the synthesis and release of Nitric Oxide by activated macrophages (Ruggiero M G. M., 2014 Sept 18-20). Counteracts the neuronal damage induced by Oxaliplatin [Chemotherapy] (Morucci G B. J., 2015 Feb).

Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms

This provides the framework for a discussion of how zebrafish may be leveraged in the future to provide novel toxicological and therapeutic insights in the field of Artificial Neural Network to Predict Varicocele Impact on Male Impact on Male Fertility through Testicular Endocannabinoid Gene Expression Profiles DavidePerruzza ,1 NicolaBernabò ,1 CinziaRapino ,2 LucaValbonetti,1 IlariaFalanga,1 ValentinaRusso,1 AnnunziataMauro ,1 PaoloBerardinelli,1 LiborioStuppia,3 MauroMaccarrone ,4,5 andBarbaraBarboni 1 The endocannabinoid gene faah2a modulates stress-associated The endocannabinoid gene faah2a modulates stress-associated behavior in zebrafish PLOS ONE , Nov 2019 Randall G. Krug , Han B. Lee , Louis Y. El Khoury , Ashley N. Sigafoos , Morgan O. Petersen , Karl J. Clark Endocannabinoid signaling in reward and addiction - Europe PMC Brain endocannabinoid signaling influences the motivation for natural rewards (such as palatable food, sexual activity and social interaction) and modulates the rewarding effects of addictive drugs. Pathological forms of natural and drug-induced reward Gene expression analysis indicates CB1 receptor upregulation in Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 weeks after single-dose MDMA administration in Dark Agouti rats A Common Polymorphism in the Cannabinoid Receptor 1 (CNR1) Gene Antipsychotic-induced weight gain has emerged as a serious complication in the treatment of patients with atypical antipsychotic drugs. The cannabinoid receptor 1 (CNR1) is expressed centrally in openSNP | rs1049353 rs1049353 T/T No summary provided. Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here.

Endocannabinoid system: Role in depression, reward and pain

(PDF) Evolutionary origins of the endocannabinoid system Evolutionary origins of the endocannabinoid system . Article (PDF Available) in Gene 370(1):64-74 · April 2006 with 1,250 Reads How we measure 'reads' A 'read' is counted each time someone views The association of endocannabinoid receptor genes (CNR1 and : Any endocannabinoid gene single-nucleotide polymorphisms (SNPs) that were reported by <2 studies were omitted. Eventually, 7 studies (with 827 depression people and 917 controls) performed between 2001 and 2015 were chosen in our meta-analysis, covering 3 gene SNPs (CNR1rs1049353, CNR1 AAT triplet repeat polymorphism, and CNR2rs2501432).

Die gleichen Forscher fanden vier Jahre später heraus, dass Endocannabinoid-Gene vermutlich zur biologischen Anfälligkeit für ein gestörtes Essverhalten beitragen können. Gerade in diesem Gebiet sind weitere Forschungen und Untersuchungen notwendig.

Eventually, 7 studies (with 827 depression people and 917 controls) performed between 2001 and 2015 were chosen in our meta-analysis, covering 3 gene SNPs (CNR1rs1049353, CNR1 AAT triplet repeat polymorphism, and CNR2rs2501432). Wie kann Medizinalhanf bei Essstörungen helfen? Die gleichen Forscher fanden vier Jahre später heraus, dass Endocannabinoid-Gene vermutlich zur biologischen Anfälligkeit für ein gestörtes Essverhalten beitragen können. Gerade in diesem Gebiet sind weitere Forschungen und Untersuchungen notwendig. Denn sollte sich die Annahme bestätigen, so könnte Cannabis als Medizin bei Patienten Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms Experimental data suggest that the endogenous cannabinoid system is involved in mood regulation, but no study has been performed so far to investigate the role of endocannabinoid genes in the susceptibility to major depression (MD) and/or bipolar disorder (BD). Association of CNR1 and FAAH endocannabinoid gene polymorphisms To the best of our knowledge, this is the first study investigating endocannabinoid gene SNPs in BN; therefore, our findings are not comparable to literature data and need to be confirmed in future studies. The mechanisms through which these SNPs may predispose to both AN and BN are not easily understandable.

CBD For Bipolar: Can Cannabinoids Help Treat Bipolar Affective An investigation of endocannabinoid gene variants in 83 patients with major depressive disorder (MDD), 134 with BPAD, and 117 healthy control participants found two marked differences in the patients afflicted with MDD and BPAD. Specifically, the CB1 receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes of the ill participants were found Systems Biology Analysis of the Endocannabinoid System Reveals a Abstract We represented the endocannabinoid system (ECS) as a biological network, where ECS molecules are the nodes (123) and their interactions the links (189). ECS network follows a scale-free to Bipolar disorder and the endocannabinoid system | Acta Bipolar disorder and the endocannabinoid system - Shokouh Arjmand, Mina Behzadi, Kristi A. Kohlmeier, Shahrzad Mazhari, Abdolreza Sabahi, Mohammad Shabani Elucidating cannabinoid biology in zebrafish (Danio rerio) - These results are considered in the context of either endocannabinoid gene expression or endocannabinoid gene function, and are integrated with findings from rodent studies. This provides the framework for a discussion of how zebrafish may be leveraged in the future to provide novel toxicological and therapeutic insights in the field of Artificial Neural Network to Predict Varicocele Impact on Male The relationship between varicocele and fertility has always been a matter of debate because of the absence of predictive clinical indicators or molecular markers able to define the severity of this disease. Even though accumulated evidence demonstrated that the endocannabinoid system (ECS) plays a central role in male reproductive biology, particularly in the testicular compartment, to date The role of endocannabinoids in the control of eating disorders Monteleone P, Bifulco M, Di Filippo C, Gazzerro P, Canestrelli B, et al. (2009) Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effects.

Counteracts the neuronal damage induced by Oxaliplatin [Chemotherapy] (Morucci G B. J., 2015 Feb). CBD For Bipolar Disorder: Can Cannabinoids Help Treat - The An investigation of endocannabinoid gene variants in 83 patients with major depressive disorder (MDD), 134 with BPAD, and 117 healthy control participants found two marked differences in the patients afflicted with MDD and BPAD. Specifically, the CB1 receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes of the ill participants were found Contribution of Endocannabinoid Gene Expression and Genotype on Background:A major research emphasis has been focused on defining the molecular changes that occur from acute to chronic pain to identify potential therapeutic targets for chronic pain. CBD For Bipolar: Can Cannabinoids Help Treat Bipolar Affective An investigation of endocannabinoid gene variants in 83 patients with major depressive disorder (MDD), 134 with BPAD, and 117 healthy control participants found two marked differences in the patients afflicted with MDD and BPAD. Specifically, the CB1 receptor (CNR1) and fatty acid amide hydrolase (FAAH) genes of the ill participants were found Systems Biology Analysis of the Endocannabinoid System Reveals a Abstract We represented the endocannabinoid system (ECS) as a biological network, where ECS molecules are the nodes (123) and their interactions the links (189). ECS network follows a scale-free to Bipolar disorder and the endocannabinoid system | Acta Bipolar disorder and the endocannabinoid system - Shokouh Arjmand, Mina Behzadi, Kristi A. Kohlmeier, Shahrzad Mazhari, Abdolreza Sabahi, Mohammad Shabani Elucidating cannabinoid biology in zebrafish (Danio rerio) - These results are considered in the context of either endocannabinoid gene expression or endocannabinoid gene function, and are integrated with findings from rodent studies.

AU - Krug, Randall G. AU - Lee, Han B. AU - El Khoury, Louis Y. Genetic variability in the endocannabinoid system and 12-week Monteleone, P, Bifulco, M, Maina, G. (2010) Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms in bipolar disorder and major depression. The genetic basis of the endocannabinoid system and drug The cannabinoid receptor (CNR1) and the fatty acid amide hydrolase (FAAH) genes are located on chromosomes 6 and 1 in the 6q15 and 1p33 cytogenetic bands, respectively. Contributions of endocannabinoid signaling to psychiatric Canna~Fangled Abstracts Contributions of endocannabinoid signaling to psychiatric disorders in humans: Genetic and biochemical evidence Contribution of Endocannabinoid Gene Expression and Genotype on A major research emphasis has been focused on defining the molecular changes that occur from acute to chronic pain to identify potential therapeutic targets for chronic pain. Zebrafish as a High-Throughput In Vivo Model for Testing the Zebrafish express both CB1 and CB2 receptors along with all of the other major endocannabinoid-related genes.

CrossRef PubMed Google Scholar Contribution of Endocannabinoid Gene Expression and Genotype : ribute to chronic pain vulnerability involves alterations in the amount of circulating endocannabinoids. Therefore, this study sought to examine cannabinoid type 1 (CNR1), type 2 (CNR2) receptors, fatty acid amide hydrolase (FAAH), and the vanilloid receptor (transient receptor potential cation channel subfamily V member 1 [TRPV1]) gene expression profiles among individuals with acute and FABP-1 gene ablation impacts brain endocannabinoid system in male Abstract. Liver fatty acid-binding protein (FABP1, L-FABP) has high affinity for and enhances uptake of arachidonic acid (ARA, C20:4, n-6) which, when esterified to phospholipids, The endocannabinoid gene faah2a modulates stress-associated The endocannabinoid gene faah2a modulates stress-associated behavior in zebrafish rs1049353 - SNPedia [PMID 20080186] Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms in bipolar disorder and major depression. [ PMID 20192949 ] CNR1 gene polymorphisms in addictive disorders: a systematic review and a meta-analysis. A polymorphism in the gene of the endocannabinoid - The endocannabinoid (eCB) system is implicated in several psychiatric disorders.